![]() However, the bodies protective system or negative feedback system then activates to normalize the metabolism and body temperature back to normal. This causes an increased thermogenic effect, thus raising body temperature and increasing the user’s metabolism in conjunction with the rest of the stack (Caffeine and Aspirin). This increases the circulating nor-epinephrine in the body, which then acts on white Adipose tissue (fatty tissue to me and you) by increasing cAMP (Cyclic Adenosine MonoPhosphate) levels. Ephedrine stimulates the release of both nor-epinephrine and adrenaline into your system. To listen to any of the past episodes for free, check out this page.The effects of the Legendary ECA Stack ( Ephedrine, Caffeine and Aspirin sometimes includes Naringin or Grapefruit extract) in weight loss are primarily due to the Ephedrine HCL component but not the reason by any measure. It has been selected for "Best of Apple Podcasts" three times, it is often the #1 interview podcast across all of Apple Podcasts, and it's been ranked #1 out of 400,000+ podcasts on many occasions. The Tim Ferriss Show is one of the most popular podcasts in the world with more than 900 million downloads. Bloodthinning compounds ain’t for babies. If you are pregnant or breastfeeding, do not use PAGG. In particular, blood-thinning medications (e.g., warfarin, aspirin, etc.), thyroid medications, or anti-anxiety drugs like clozapine. In the meantime, here are the basic precautions and warnings:Įnsure adequate consumption of B-complex vitamins while using PAGG and consult your doctor before use if you have a medical condition (e.g., hypertension, hypoglycemia, diabetes) or are taking any medications. I will be writing much more extensively on detailed use of PAGG™ - as well as other options for reducing and eliminating stimulant use - in the coming months. The end result was a stimulant-free supplement I created and call PAGG™. I wanted to find a nonstimulant stack that used different pathways altogether. It was clear that another fat-loss approach was needed, something more sustainable. From that point onward, I removed stimulants for brief but increasing periods, as painful as it was, until I had reestablished basic adrenal function. She was amazed that I was able to get out of bed in the morning. I suffered so many sinus infections post-ECA that I visited a Stanford-trained specialist who, after reviewing a cranial MRI, asked without a second of hesitation: “Do you drink much caffeine or take other stimulants?” Almost all of my sinal cavities were completely blocked with compressed, dried matter. Used in high doses or in high-humidity/ high-heat conditions, ephedrine and ephedra have both been associated with heart attack and death. I suspect there is an entire generation of strength and endurance athletes with ECA-induced adrenal fatigue who now depend on stimulants for normal everyday function-some I know opt for 6–10 double espressos per 24 hours. Either people never stop taking ECA or they substitute in equally strong drugs to avoid chronic fatigue. The withdrawal pains lead to a domino effect of stimulant use. ![]() Tolerance to the upper-like effects develops quickly and cessation can cause severe headaches. The effects are beautiful and predictable, but there are prices to be paid: side effects. In fact, In over-the-counter drugs, ephedrine is generally mixed with guafenesin (an expectorant), as it can otherwise be freebased with basic lab supplies into methamphetamine. The ephedrine increases cAMP levels, the caffeine slows cAMP breakdown, and the aspirin further helps sustain increased cAMP levels by inhibiting prostagladin production. If E = 1, C = 1, and A = 1, the three combined have a synergistic effect of 1 + 1 + 1 = 6–10. The biochemistry was spot-on, and dozens of studies supported the effects. This was the mixture I used three times per day when on the Cyclical Ketogenic Diet to produce veins on my abdomen for the first time in my life, all in less than eight weeks. From 1995 to 2000, I experimented with a fat-loss cocktail that comprised ephedrine hydrochloride, caffeine, and aspirin-the famed and research-proven “ECA” stack.
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